rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
5
|
pubmed:dateCreated |
2007-5-7
|
pubmed:abstractText |
Anaplastic thyroid carcinoma (ATC) is one of the most aggressive types of cancer characterized by complete refractoriness to multimodal treatment approaches. Therapeutic strategies based on the simultaneous use of proteasome inhibitors and death receptor ligands have been shown to induce apoptosis in several tumor types but have not yet been explored in ATC.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
AIM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
May
|
pubmed:issn |
0021-972X
|
pubmed:author |
pubmed-author:AdamoLuanaL,
pubmed-author:AnastasiGabrieleG,
pubmed-author:ConticelloConcettaC,
pubmed-author:De MariaRuggeroR,
pubmed-author:EramoAdrianaA,
pubmed-author:GiuffridaDarioD,
pubmed-author:GiuffridaRaffaellaR,
pubmed-author:GulisanoMassimoM,
pubmed-author:IannoloGioacchinG,
pubmed-author:MemeoLorenzoL,
pubmed-author:VicariLuisaL,
pubmed-author:ZeunerAnnA
|
pubmed:issnType |
Print
|
pubmed:volume |
92
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1938-42
|
pubmed:meshHeading |
pubmed-meshheading:17327374-Apoptosis,
pubmed-meshheading:17327374-Boronic Acids,
pubmed-meshheading:17327374-Carcinoma,
pubmed-meshheading:17327374-Caspases,
pubmed-meshheading:17327374-Cell Cycle,
pubmed-meshheading:17327374-Cell Line, Tumor,
pubmed-meshheading:17327374-Cell Survival,
pubmed-meshheading:17327374-Flow Cytometry,
pubmed-meshheading:17327374-Humans,
pubmed-meshheading:17327374-Immunohistochemistry,
pubmed-meshheading:17327374-Proteasome Endopeptidase Complex,
pubmed-meshheading:17327374-Pyrazines,
pubmed-meshheading:17327374-Retroviridae,
pubmed-meshheading:17327374-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:17327374-TNF-Related Apoptosis-Inducing Ligand,
pubmed-meshheading:17327374-Thyroid Neoplasms
|
pubmed:year |
2007
|
pubmed:articleTitle |
Proteasome inhibitors synergize with tumor necrosis factor-related apoptosis-induced ligand to induce anaplastic thyroid carcinoma cell death.
|
pubmed:affiliation |
Department of Experimental Oncology, Meditteranean Institute of Oncology, 95029 Viagrande, Catania, Italy.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|