rdf:type |
|
lifeskim:mentions |
umls-concept:C0011860,
umls-concept:C0080103,
umls-concept:C0178665,
umls-concept:C0181586,
umls-concept:C0205329,
umls-concept:C0332271,
umls-concept:C0332307,
umls-concept:C0542341,
umls-concept:C0681850,
umls-concept:C1517945,
umls-concept:C1550501,
umls-concept:C1706203,
umls-concept:C2349001,
umls-concept:C2697811
|
pubmed:issue |
3
|
pubmed:dateCreated |
2007-2-28
|
pubmed:abstractText |
The relative roles of insulin resistance and beta-cell dysfunction in the pathogenesis of impaired glucose tolerance (IGT) and type 2 diabetes are debated. First-degree relatives of individuals with type 2 diabetes are at increased risk of developing hyperglycemia.
|
pubmed:grant |
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Mar
|
pubmed:issn |
1935-5548
|
pubmed:author |
|
pubmed:issnType |
Electronic
|
pubmed:volume |
30
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
677-82
|
pubmed:dateRevised |
2011-11-17
|
pubmed:meshHeading |
pubmed-meshheading:17327340-Adiponectin,
pubmed-meshheading:17327340-Adult,
pubmed-meshheading:17327340-Blood Glucose,
pubmed-meshheading:17327340-Body Mass Index,
pubmed-meshheading:17327340-Body Size,
pubmed-meshheading:17327340-Diabetes Mellitus, Type 2,
pubmed-meshheading:17327340-Family,
pubmed-meshheading:17327340-Follow-Up Studies,
pubmed-meshheading:17327340-Glucose Intolerance,
pubmed-meshheading:17327340-Glucose Tolerance Test,
pubmed-meshheading:17327340-Humans,
pubmed-meshheading:17327340-Insulin,
pubmed-meshheading:17327340-Insulin Resistance,
pubmed-meshheading:17327340-Insulin-Secreting Cells,
pubmed-meshheading:17327340-Middle Aged,
pubmed-meshheading:17327340-Prediabetic State,
pubmed-meshheading:17327340-Risk Factors,
pubmed-meshheading:17327340-Sensitivity and Specificity,
pubmed-meshheading:17327340-Weight Gain
|
pubmed:year |
2007
|
pubmed:articleTitle |
Progressive loss of beta-cell function leads to worsening glucose tolerance in first-degree relatives of subjects with type 2 diabetes.
|
pubmed:affiliation |
Division of Metabolism, Endocrinology, and Nutrition, Department of Medicine, VA Puget Sound Health Care System and University of Washington, Seattle, Washington 98108, USA.
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
|