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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2008-2-29
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pubmed:abstractText |
Hepatic lipase (HL) catalyzes the hydrolysis of triglycerides and phospholipids from lipoproteins, and promotes the hepatic uptake of lipoproteins. A common G-250A polymorphism in the promoter of the hepatic lipase gene (LIPC) has been described. The aim was to study the effects of the G-250A polymorphism on HL activity, serum lipid profile and insulin sensitivity.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Blood Glucose,
http://linkedlifedata.com/resource/pubmed/chemical/Cholesterol, LDL,
http://linkedlifedata.com/resource/pubmed/chemical/Dietary Fats,
http://linkedlifedata.com/resource/pubmed/chemical/Fatty Acids,
http://linkedlifedata.com/resource/pubmed/chemical/Fatty Acids, Monounsaturated,
http://linkedlifedata.com/resource/pubmed/chemical/Fish Oils,
http://linkedlifedata.com/resource/pubmed/chemical/Insulin,
http://linkedlifedata.com/resource/pubmed/chemical/Lipase,
http://linkedlifedata.com/resource/pubmed/chemical/hepatic lipase, human
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
1590-3729
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pubmed:author |
pubmed-author:HermansenKjeldK,
pubmed-author:KANWU Study Group,
pubmed-author:LaaksoMarkkuM,
pubmed-author:LindiVirpiV,
pubmed-author:LouherantaAnneA,
pubmed-author:RiccardiGabrieleG,
pubmed-author:RivelleseAngela AAA,
pubmed-author:SchwabUrsulaU,
pubmed-author:TapsellLindaL,
pubmed-author:UusitupaMatti I JMI,
pubmed-author:VessbyBengtB
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pubmed:issnType |
Electronic
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pubmed:volume |
18
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
88-95
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:17327141-Adult,
pubmed-meshheading:17327141-Australia,
pubmed-meshheading:17327141-Blood Glucose,
pubmed-meshheading:17327141-Cholesterol, LDL,
pubmed-meshheading:17327141-Dietary Fats,
pubmed-meshheading:17327141-Europe,
pubmed-meshheading:17327141-Fatty Acids,
pubmed-meshheading:17327141-Fatty Acids, Monounsaturated,
pubmed-meshheading:17327141-Female,
pubmed-meshheading:17327141-Fish Oils,
pubmed-meshheading:17327141-Gene Expression Regulation, Enzymologic,
pubmed-meshheading:17327141-Gene Frequency,
pubmed-meshheading:17327141-Genetic Predisposition to Disease,
pubmed-meshheading:17327141-Humans,
pubmed-meshheading:17327141-Hypercholesterolemia,
pubmed-meshheading:17327141-Insulin,
pubmed-meshheading:17327141-Insulin Resistance,
pubmed-meshheading:17327141-Lipase,
pubmed-meshheading:17327141-Liver,
pubmed-meshheading:17327141-Male,
pubmed-meshheading:17327141-Middle Aged,
pubmed-meshheading:17327141-Phenotype,
pubmed-meshheading:17327141-Polymorphism, Single Nucleotide,
pubmed-meshheading:17327141-Postprandial Period,
pubmed-meshheading:17327141-Promoter Regions, Genetic,
pubmed-meshheading:17327141-Time Factors
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pubmed:year |
2008
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pubmed:articleTitle |
The G-250A polymorphism in the hepatic lipase gene promoter is associated with changes in hepatic lipase activity and LDL cholesterol: The KANWU Study.
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pubmed:affiliation |
University of Kuopio, Department of Clinical Nutrition, P.O. Box 1627, FIN-70211 Kuopio, Finland.
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pubmed:publicationType |
Journal Article,
Randomized Controlled Trial,
Multicenter Study
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