17325656

Source:http://linkedlifedata.com/resource/pubmed/id/17325656

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0035804, umls-concept:C0441655, umls-concept:C0971858, umls-concept:C1512474, umls-concept:C1515655
pubmed:issue	7
pubmed:dateCreated	2007-4-2
pubmed:abstractText	Rheumatoid arthritis (RA) is a chronic inflammatory disease. Histone deacetylase inhibitors (HDACi), a new class of anti-cancer agents, have recently been reported to exhibit potent anti-inflammatory activities. A proof of concept study was carried out with suberoylanilide hydroxamic acid (SAHA) and MS-275, two HDACi currently undergoing clinical investigations for various oncological indications.
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pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/7502536
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Antirheumatic Agents, http://linkedlifedata.com/resource/pubmed/chemical/Benzamides, http://linkedlifedata.com/resource/pubmed/chemical/Histone Deacetylase Inhibitors, http://linkedlifedata.com/resource/pubmed/chemical/Hydroxamic Acids, http://linkedlifedata.com/resource/pubmed/chemical/Interleukin-1beta, http://linkedlifedata.com/resource/pubmed/chemical/Interleukin-6, http://linkedlifedata.com/resource/pubmed/chemical/N-(2-aminophenyl)-4-(N-(pyridin-3-yl..., http://linkedlifedata.com/resource/pubmed/chemical/Pyridines, http://linkedlifedata.com/resource/pubmed/chemical/vorinostat
pubmed:status	MEDLINE
pubmed:month	Apr
pubmed:issn	0007-1188
pubmed:author	pubmed-author:BOURGOINLL, pubmed-author:BaronRR, pubmed-author:BastianelliEE, pubmed-author:ChanH-YHY, pubmed-author:HoranFrankF, pubmed-author:HuC-YCY, pubmed-author:HuangH-PHP, pubmed-author:LepescheuxLL, pubmed-author:LiuH-LHL, pubmed-author:RawadiGG
pubmed:issnType	Print
pubmed:volume	150
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	862-72
pubmed:dateRevised	2011-8-25
pubmed:meshHeading	pubmed-meshheading:17325656-Animals, pubmed-meshheading:17325656-Antirheumatic Agents, pubmed-meshheading:17325656-Arthritis, Experimental, pubmed-meshheading:17325656-Arthritis, Rheumatoid, pubmed-meshheading:17325656-Benzamides, pubmed-meshheading:17325656-Female, pubmed-meshheading:17325656-Histone Deacetylase Inhibitors, pubmed-meshheading:17325656-Hydroxamic Acids, pubmed-meshheading:17325656-Interleukin-1beta, pubmed-meshheading:17325656-Interleukin-6, pubmed-meshheading:17325656-Male, pubmed-meshheading:17325656-Metatarsal Bones, pubmed-meshheading:17325656-Mice, pubmed-meshheading:17325656-Mice, Inbred DBA, pubmed-meshheading:17325656-Pyridines, pubmed-meshheading:17325656-Rats, pubmed-meshheading:17325656-Rats, Inbred Strains
pubmed:year	2007
pubmed:articleTitle	Anti-rheumatic activities of histone deacetylase (HDAC) inhibitors in vivo in collagen-induced arthritis in rodents.
pubmed:affiliation	Proskelia a Galapagos Company, Romainville, France.
pubmed:publicationType	Journal Article, Comparative Study

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