Linked Life Data

17321333

Source:http://linkedlifedata.com/resource/pubmed/id/17321333

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2007-2-26
pubmed:abstractText
A reciprocal t(X;12)(p11;p13) was found as the sole clonal abnormality in biphenotypic leukemia with myeloid and B-lymphoid differentiation. With fluorescence in situ hybridization analysis, the ETV6 gene (previously TEL) was found to be translocated intact to the derivative X chromosome; no MLL and BCR/ABL rearrangements were found. The patient achieved complete remission after induction chemotherapy. To our knowledge, this cytogenetic aberration has not been reported previously as a sole abnormality in hematological malignancies. Its presence may suggest an important role in the pathogenesis of biphenotypic leukemia.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0165-4608
pubmed:author
pubmed:issnType
Print
pubmed:volume
173
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
159-63
pubmed:meshHeading
pubmed:year
2007
pubmed:articleTitle
Translocation (X;12)(p11;p13) as a sole abnormality in biphenotypic acute leukemia.
pubmed:affiliation
Laboratory of Health Physics and Environmental Hygiene, National Center for Scientific Research (NCSR) Demokritos, 15310 Aghia Paraskevi, Athens, Greece. pmanola@ipta.demokritos.gr
pubmed:publicationType
Journal Article, Case Reports