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rdf:type |
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lifeskim:mentions |
umls-concept:C0008651,
umls-concept:C0017337,
umls-concept:C0023270,
umls-concept:C0205147,
umls-concept:C0205314,
umls-concept:C0678594,
umls-concept:C0679622,
umls-concept:C0887950,
umls-concept:C1514562,
umls-concept:C1519249,
umls-concept:C1704973,
umls-concept:C1707455,
umls-concept:C1707719,
umls-concept:C2348519
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pubmed:dateCreated |
2007-3-1
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pubmed:databankReference |
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/DQ522034,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/DQ522035,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/DQ522036,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/DQ522037,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/DQ522038,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/DQ522039,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/DQ522040,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/DQ522041,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/DQ522042,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/DQ522043,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/DQ522044,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/DQ522045,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/DQ522046,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/DQ522047,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/DQ522048
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pubmed:abstractText |
Trypanosomatids exhibit a unique gene organization into large directional gene clusters (DGCs) in opposite directions. The transcription "strand switch region" (SSR) separating the two large DGCs that constitute chromosome 1 of Leishmania major has been the subject of several studies and speculations. Thus, it has been suspected of being the single replication origin of the chromosome, the transcription initiation site for both DGCs or even a centromere. Here, we have used an inter-species compared genomics approach on this locus in order to try to identify conserved features or motifs indicative of a putative function.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/17319967-10077609,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17319967-10352176,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17319967-10748898,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17319967-10904419,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17319967-10908338,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17319967-11013754,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17319967-11727994,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17319967-11811799,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17319967-12003487,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17319967-12036593,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17319967-12202753,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17319967-12769852,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17319967-12853638,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17319967-15510221,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17319967-15632088,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17319967-16020724,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17319967-16020728,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17319967-16079225,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17319967-16430691,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17319967-2080829,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17319967-8227199,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17319967-8649987,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17319967-8650178,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17319967-8915125,
http://linkedlifedata.com/resource/pubmed/commentcorrection/17319967-9813266
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:issn |
1471-2164
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
8
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
57
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:17319967-Animals,
pubmed-meshheading:17319967-Chromosomes,
pubmed-meshheading:17319967-DNA, Protozoan,
pubmed-meshheading:17319967-Genes, Protozoan,
pubmed-meshheading:17319967-Genomics,
pubmed-meshheading:17319967-Leishmania,
pubmed-meshheading:17319967-Molecular Sequence Data,
pubmed-meshheading:17319967-Phylogeny,
pubmed-meshheading:17319967-Polymerase Chain Reaction,
pubmed-meshheading:17319967-Sequence Analysis, DNA,
pubmed-meshheading:17319967-Species Specificity
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pubmed:year |
2007
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pubmed:articleTitle |
Compared genomics of the strand switch region of Leishmania chromosome 1 reveal a novel genus-specific gene and conserved structural features and sequence motifs.
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pubmed:affiliation |
CNRS/Université Montpellier, Biologie Moléculaire, Biologie Cellulaire et Biodiversité des Protozoaires Parasites, Laboratoire de Parasitologie-Mycologie, UFR Médecine, Montpellier, France. jacques.puechberty@igh.cnrs.fr
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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