Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
1992-2-27
pubmed:abstractText
In tomato, resistance to the wilt fungus Verticillium albo-atrum is determined primarily by the Ve locus. When two tomato near-isolines which differ at this locus and in their susceptibility to the pathogen were compared, more rapid suberin coating in the xylem of resistant plants correlated closely with a more rapid increase in the activity of phenylalanine ammonia-lyase (PAL; EC 4.3.1.5), an enzyme which is essential to the suberization process. In contrast, levels of mRNA did not increase proportionally to the measured enzyme activities; rather, there was a substantial suppression of mRNA levels in the susceptible tomato line, consistent with a much lower elevation of PAL activity and significantly less vascular coating. The suppression was absent or substantially reduced in the resistant line. The results indicate that the pathogen can suppress defense genes in susceptible plants but suggest that their expression is altered in resistant hosts and that post-transcriptional regulation plays a significant role.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
0167-4412
pubmed:author
pubmed:issnType
Print
pubmed:volume
18
pubmed:geneSymbol
PAL
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
345-52
pubmed:dateRevised
2009-11-19
pubmed:meshHeading
pubmed:year
1992
pubmed:articleTitle
Reduced PAL gene suppression in Verticillium-infected resistant tomatoes.
pubmed:affiliation
Department of Molecular Biology and Genetics, University of Guelph, Ontario, Canada.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't