Source:http://linkedlifedata.com/resource/pubmed/id/17318877
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
2007-2-28
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pubmed:abstractText |
Substantial evidence supports a direct role of ornithine decarboxylase (ODC) in the development and maintenance of human tumors. Although antisense oligonucleotide therapy targeting various genes are useful for cancer treatment, 1 of the major limitations is the problem of delivery. A novel antisense oligonucleotide delivery method is described that allows prolonged sustainment and release of ODC antisense oligonucleotides in vivo using atelocollagen.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0008-543X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
109
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
993-1002
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pubmed:meshHeading |
pubmed-meshheading:17318877-Animals,
pubmed-meshheading:17318877-Cell Line, Tumor,
pubmed-meshheading:17318877-Cell Proliferation,
pubmed-meshheading:17318877-Collagen,
pubmed-meshheading:17318877-Drug Delivery Systems,
pubmed-meshheading:17318877-Humans,
pubmed-meshheading:17318877-Mice,
pubmed-meshheading:17318877-Mice, Nude,
pubmed-meshheading:17318877-Neoplasms, Experimental,
pubmed-meshheading:17318877-Oligonucleotides, Antisense,
pubmed-meshheading:17318877-Ornithine Decarboxylase
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pubmed:year |
2007
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pubmed:articleTitle |
Single-injection ornithine decarboxylase-directed antisense therapy using atelocollagen to suppress human cancer growth.
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pubmed:affiliation |
Department of Physiological Chemistry and Metabolism, Graduate School of Medicine, University of Tokyo, Tokyo, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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