Source:http://linkedlifedata.com/resource/pubmed/id/17318659
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
2007-3-29
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pubmed:abstractText |
To describe the serotonergic system in a tunicate larva, we cloned a gene encoding for tryptophan hydroxylase (TPH), the rate-limiting enzyme in serotonin synthesis, in the ascidian Ciona intestinalis and studied its expression pattern during development. Ci-TPH expression was found from tailbud stage in the precursor cells of the visceral ganglion and in the tail. In the larva, TPH-expressing neurons formed two clusters in the anterior central nervous system at the level of the visceral ganglion. Moreover, we found Ci-TPH expression at the level of the muscle cells of the tail and suggested that this localisation might be at the level of neuro-muscular junctions. Moreover, we discussed the involvement of serotonin in the control of larval locomotory activity.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0949-944X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
217
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
307-13
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pubmed:meshHeading |
pubmed-meshheading:17318659-Amino Acid Sequence,
pubmed-meshheading:17318659-Animals,
pubmed-meshheading:17318659-Ciona intestinalis,
pubmed-meshheading:17318659-Embryo, Nonmammalian,
pubmed-meshheading:17318659-Gene Expression Regulation, Developmental,
pubmed-meshheading:17318659-Gene Expression Regulation, Enzymologic,
pubmed-meshheading:17318659-Molecular Sequence Data,
pubmed-meshheading:17318659-Phylogeny,
pubmed-meshheading:17318659-Sequence Analysis, DNA,
pubmed-meshheading:17318659-Tryptophan Hydroxylase
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pubmed:year |
2007
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pubmed:articleTitle |
Developmental expression of tryptophan hydroxylase gene in Ciona intestinalis.
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pubmed:affiliation |
Dipartimento di Biologia, Università di Milano, via Celoria 26, 20133 Milano, Italy. roberta.pennati@unimi.it
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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