|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
1
|
|
pubmed:dateCreated |
1992-2-18
|
|
pubmed:abstractText |
Rabbit skeletal muscle membranes contain a protein which inhibits the cAMP-dependent protein kinase. The activity of the partially purified membrane protein is characterized by an IC-50 of 10 to 30 nM with respect to the inhibition of the activity of the catalytic subunit of the cAMP-dependent protein kinase and is sensitive to treatment with heat, acid, alkali and trypsin. The active fractions contain proteins ranging from 40 to 120 kDa, analysed by SDS-gel electrophoresis.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Jan
|
|
pubmed:issn |
0006-291X
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
|
|
pubmed:day |
15
|
|
pubmed:volume |
182
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
232-7
|
|
pubmed:dateRevised |
2006-11-15
|
|
pubmed:meshHeading |
pubmed-meshheading:1731783-Animals,
pubmed-meshheading:1731783-Carrier Proteins,
pubmed-meshheading:1731783-Chromatography, Affinity,
pubmed-meshheading:1731783-Chromatography, Gel,
pubmed-meshheading:1731783-Chromatography, Ion Exchange,
pubmed-meshheading:1731783-Intracellular Signaling Peptides and Proteins,
pubmed-meshheading:1731783-Kinetics,
pubmed-meshheading:1731783-Membrane Proteins,
pubmed-meshheading:1731783-Molecular Weight,
pubmed-meshheading:1731783-Muscles,
pubmed-meshheading:1731783-Protein Kinase Inhibitors,
pubmed-meshheading:1731783-Rabbits
|
|
pubmed:year |
1992
|
|
pubmed:articleTitle |
Characterization and partial purification of a membrane protein from rabbit skeletal muscle which inhibits the cAMP-dependent protein kinase.
|
|
pubmed:affiliation |
Institute of Molecular Cell Biology, University of Freiburg, Germany.
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
