Linked Life Data

17316824

Source:http://linkedlifedata.com/resource/pubmed/id/17316824

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2007-7-13
pubmed:abstractText
Sleep studies in patients with obsessive compulsive disorder (OCD) are sparse and results inconsistent. Moreover, in 3 out of 4 published studies up to 50% of patients suffered from secondary major depression. In this study, 10 inpatients with a DSM-IV diagnosis of OCD without comorbid major depression (Yale-Brown Obsessive Compulsive Scale (Y-BOCS) score >15; Hamilton Depression Rating Scale (HAMD)-21 total score <17) and 10 healthy matched controls were included. Polysomnography of patients (7 males, 3 females, 34.5+/-12.7 years, Y-BOCS: 27.8+/-4.6, HAMD-21: 13.3+/-1.9) and controls (7 males, 3 females, 34.4+/-12.8 years) was recorded, following an adaptation night. Sleep variables did not significantly differ in both groups except that stage 4 sleep was reduced in patients. Three of the patients with OCD, however, exhibited sleep onset REM periods (SOREMPs), i.e. rapid-eye-movement (REM) latencies <10 min. Obsessive compulsive symptoms were significantly (P<0.05) more severe in these patients (Y-BOCS: 32+/-2.0) compared to those without SOREMPs (Y-BOCS 26+/-4.2). This is, to our knowledge, the first report of sleep onset REM periods in OCD.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0165-1781
pubmed:author
pubmed:issnType
Print
pubmed:day
30
pubmed:volume
152
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
29-35
pubmed:dateRevised
2008-4-17
pubmed:meshHeading
pubmed:year
2007
pubmed:articleTitle
Sleep onset REM periods in obsessive compulsive disorder.
pubmed:affiliation
Max Planck Institute of Psychiatry, Munich, Germany. kluge@mpipsykl.mpg.de
pubmed:publicationType
Journal Article