Source:http://linkedlifedata.com/resource/pubmed/id/17315959
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2007-2-23
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pubmed:abstractText |
Bioassay-guided fractionation of the 7:3 MeOH/water extract of a cultured cyanobacterium strain identified as Fischerella sp. yielded nine isonitrile-containing alkaloids. Three of the compounds, ambiguine H isonitrile (1), ambiguine I isonitrile (2), and ambiguine J isonitrile (3), are new, while the other six, 12-epi-hapalindole H, ambiguine A isonitrile, ambiguine B isonitrile, ambiguine D isonitrile, ambiguine E isonitrile, and ambiguine F isonitrile, have been previously isolated from Fischerella ambigua. The structures of the compounds were determined by 1D and 2D NMR techniques and mass spectrometric data. Ambiguine H isonirile and ambiguine I isonirile possess antibacterial and antimycotic activity.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0163-3864
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
70
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
196-201
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:17315959-Antifungal Agents,
pubmed-meshheading:17315959-Cyanobacteria,
pubmed-meshheading:17315959-Indole Alkaloids,
pubmed-meshheading:17315959-Israel,
pubmed-meshheading:17315959-Microbial Sensitivity Tests,
pubmed-meshheading:17315959-Molecular Structure,
pubmed-meshheading:17315959-Nuclear Magnetic Resonance, Biomolecular
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pubmed:year |
2007
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pubmed:articleTitle |
Antimicrobial ambiguines from the cyanobacterium Fischerella sp. collected in Israel.
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pubmed:affiliation |
School of Chemistry, Raymond and Beverly Sackler Faculty of Exact Sciences, Tel Aviv University, Ramat Aviv, Tel Aviv 69978, Israel.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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