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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2007-2-22
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pubmed:abstractText |
Anterior cingulate integrity may be required for antidepressant response. To assess anterior cingulate processes related to treatment response, we studied error-related negativity and error positivity produced during an emotional go/no-go challenge, a task activating the rostral anterior cingulate. Twelve elderly patients with major depression, treated with escitalopram 10 mg daily, were studied. Patients who remained symptomatic after 8 weeks of treatment had larger error-related negativity and smaller error positivity amplitude compared with patients who achieved remission. The error-related negativity is elicited during conflict detection and the error positivity reflects the emotional reaction to error. Thus, these findings suggest that two distinct conflict-processing functions of the anterior cingulate are important for antidepressant response of geriatric depression.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0959-4965
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
12
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pubmed:volume |
18
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
217-21
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pubmed:dateRevised |
2007-12-3
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pubmed:meshHeading |
pubmed-meshheading:17314660-Aged,
pubmed-meshheading:17314660-Aging,
pubmed-meshheading:17314660-Antidepressive Agents,
pubmed-meshheading:17314660-Brain Mapping,
pubmed-meshheading:17314660-Citalopram,
pubmed-meshheading:17314660-Decision Making,
pubmed-meshheading:17314660-Depressive Disorder, Major,
pubmed-meshheading:17314660-Electroencephalography,
pubmed-meshheading:17314660-Emotions,
pubmed-meshheading:17314660-Evoked Potentials,
pubmed-meshheading:17314660-Female,
pubmed-meshheading:17314660-Gyrus Cinguli,
pubmed-meshheading:17314660-Humans,
pubmed-meshheading:17314660-Male,
pubmed-meshheading:17314660-Neuropsychological Tests,
pubmed-meshheading:17314660-Predictive Value of Tests,
pubmed-meshheading:17314660-Remission Induction,
pubmed-meshheading:17314660-Serotonin Uptake Inhibitors,
pubmed-meshheading:17314660-Treatment Outcome
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pubmed:year |
2007
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pubmed:articleTitle |
Event-related potentials in an emotional go/no-go task and remission of geriatric depression.
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pubmed:affiliation |
Weill Medical College of Cornell University, Weill-Cornell Institute of Geriatric Psychiatry, White Plains, New York 10605, USA. gsalexop@med.cornell.edu
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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