Hyponatraemia has been shown to be an independent predictor of mortality in selected patients with heart failure enrolled in clinical trials. The predictive value of hyponatraemia has not been evaluated in unselected patients hospitalized with heart failure.
Relationship between admission serum sodium concentration and clinical outcomes in patients hospitalized for heart failure: an analysis from the OPTIMIZE-HF registry.
Division of Cardiology, Feinberg School of Medicine, Northwestern University, Galter 10-240, 201 E Huron Street, Chicago, IL 60611, USA. m-gheorghiade@northwestern.edu