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pubmed-article:17309054pubmed:abstractTextXanthohumol (XN) is a prenylated chalcone with antimutagenic and anticancer activity from hops. A nonaqueous reverse polarity capillary electrophoretic method for the determination of XN in hop extract was developed and validated. The optimal parameters were a 64.5 cm long fused-silica capillary with 50 microm id at 25 degrees C; 30 kV negative voltage (anode at detector side of the capillary); nonaqueous buffer with 75 mM NaOH and 50 mM boric acid in methanol; hydrodynamical injection with 10 mbar for 40 s; and detection at 440 nm. XN, isoxanthohumol (IX), colupulone, adlupulone, and n-lupulone were well resolved on the electropherogram. The LOD for XN was 0.05 mg/L and RSD for peak area was below 3%. The amount of XN in different samples of hop pellets varied from 0.14 to 0.42%.lld:pubmed
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pubmed-article:17309054pubmed:authorpubmed-author:JantzE MEMlld:pubmed
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pubmed-article:17309054pubmed:pagination965-9lld:pubmed
pubmed-article:17309054pubmed:dateRevised2010-11-18lld:pubmed
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pubmed-article:17309054pubmed:year2007lld:pubmed
pubmed-article:17309054pubmed:articleTitleDetermination of xanthohumol in hops (Humulus lupulus L.) by nonaqueous CE.lld:pubmed
pubmed-article:17309054pubmed:affiliationFaculty of Pharmacy, University of Ljubljana, Ljubljana, Slovenia. javor.kac@ffa.uni-lj.silld:pubmed
pubmed-article:17309054pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:17309054pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed
pubmed-article:17309054pubmed:publicationTypeEvaluation Studieslld:pubmed