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rdf:type |
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|
lifeskim:mentions |
|
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pubmed:issue |
6
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pubmed:dateCreated |
2007-4-30
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pubmed:abstractText |
Xanthohumol (XN) is a prenylated chalcone with antimutagenic and anticancer activity from hops. A nonaqueous reverse polarity capillary electrophoretic method for the determination of XN in hop extract was developed and validated. The optimal parameters were a 64.5 cm long fused-silica capillary with 50 microm id at 25 degrees C; 30 kV negative voltage (anode at detector side of the capillary); nonaqueous buffer with 75 mM NaOH and 50 mM boric acid in methanol; hydrodynamical injection with 10 mbar for 40 s; and detection at 440 nm. XN, isoxanthohumol (IX), colupulone, adlupulone, and n-lupulone were well resolved on the electropherogram. The LOD for XN was 0.05 mg/L and RSD for peak area was below 3%. The amount of XN in different samples of hop pellets varied from 0.14 to 0.42%.
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pubmed:language |
eng
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pubmed:journal |
|
|
pubmed:citationSubset |
IM
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pubmed:chemical |
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|
pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0173-0835
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:volume |
28
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
965-9
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
|
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pubmed:year |
2007
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pubmed:articleTitle |
Determination of xanthohumol in hops (Humulus lupulus L.) by nonaqueous CE.
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pubmed:affiliation |
Faculty of Pharmacy, University of Ljubljana, Ljubljana, Slovenia. javor.kac@ffa.uni-lj.si
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Evaluation Studies
|
