Source:http://linkedlifedata.com/resource/pubmed/id/17307038
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
2007-4-13
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pubmed:abstractText |
Bone mineral density has a strong genetic component but it is also influenced by environmental factors making it a complex trait to study. LRP5 gene was previously shown to be involved in rare diseases affecting bone mass. Mutations associated with gain-of-function were described as well as loss-of-function mutations. Following this discovery, many frequent LRP5 polymorphisms were tested against the variation of BMD in the normal population.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
8756-3282
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
40
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1299-307
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:17307038-Adult,
pubmed-meshheading:17307038-Aged,
pubmed-meshheading:17307038-Aged, 80 and over,
pubmed-meshheading:17307038-Bone Density,
pubmed-meshheading:17307038-Canada,
pubmed-meshheading:17307038-Female,
pubmed-meshheading:17307038-France,
pubmed-meshheading:17307038-Haplotypes,
pubmed-meshheading:17307038-Hormones,
pubmed-meshheading:17307038-Humans,
pubmed-meshheading:17307038-LDL-Receptor Related Proteins,
pubmed-meshheading:17307038-Low Density Lipoprotein Receptor-Related Protein-5,
pubmed-meshheading:17307038-Menopause,
pubmed-meshheading:17307038-Middle Aged,
pubmed-meshheading:17307038-Polymorphism, Genetic
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pubmed:year |
2007
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pubmed:articleTitle |
LRP5 coding polymorphisms influence the variation of peak bone mass in a normal population of French-Canadian women.
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pubmed:affiliation |
Unité de Recherche en Génétique Humaine et Moléculaire, Centre de Recherche de l'Hôpital St-François d'Assise du Centre Hospitalier Universitaire de Québec, Québec, Canada G1L 3L5.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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