rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
9
|
pubmed:dateCreated |
2007-4-20
|
pubmed:abstractText |
Cigarette smoking worsens asthma and is associated with reduced response to corticosteroid therapy. As cigarette smoke is known to have immunomodulatory effects, we hypothesized that one mechanism by which smoking mediates its adverse effect is by reduction of the numbers of bronchial mucosal dendritic cells (DCs), which control B-cell growth and T-cell responses.
|
pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
AIM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
May
|
pubmed:issn |
1073-449X
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:day |
1
|
pubmed:volume |
175
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
919-25
|
pubmed:dateRevised |
2008-11-21
|
pubmed:meshHeading |
pubmed-meshheading:17303795-Adolescent,
pubmed-meshheading:17303795-Adult,
pubmed-meshheading:17303795-Aged,
pubmed-meshheading:17303795-Antigens, CD,
pubmed-meshheading:17303795-Asthma,
pubmed-meshheading:17303795-Bronchi,
pubmed-meshheading:17303795-Case-Control Studies,
pubmed-meshheading:17303795-Dendritic Cells,
pubmed-meshheading:17303795-Female,
pubmed-meshheading:17303795-Humans,
pubmed-meshheading:17303795-Immunity, Mucosal,
pubmed-meshheading:17303795-Interferon-gamma,
pubmed-meshheading:17303795-Interleukin-4,
pubmed-meshheading:17303795-Male,
pubmed-meshheading:17303795-Middle Aged,
pubmed-meshheading:17303795-Respiratory Mucosa,
pubmed-meshheading:17303795-Smoking
|
pubmed:year |
2007
|
pubmed:articleTitle |
Cigarette smoking alters bronchial mucosal immunity in asthma.
|
pubmed:affiliation |
Lung Pathology Unit, Department of Gene Therapy, Imperial College London, London, UK.
|
pubmed:publicationType |
Journal Article
|