|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
7
|
|
pubmed:dateCreated |
2007-3-13
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|
pubmed:abstractText |
A library of potential antifungal triazole-modified beta-methoxyacrylate analogues was designed and synthesized via a Cu(I)-catalyzed 1,3-dipolar alkyne-azide coupling reaction or 'click chemistry'. Subsequent biological screening revealed that some compounds displayed low to moderate antifungal activity toward pathogenic fungi and low phytotoxicity.
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pubmed:language |
eng
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|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Apr
|
|
pubmed:issn |
0960-894X
|
|
pubmed:author |
|
|
pubmed:issnType |
Print
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|
pubmed:day |
1
|
|
pubmed:volume |
17
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
1979-83
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|
pubmed:meshHeading |
pubmed-meshheading:17300931-Acrylates,
pubmed-meshheading:17300931-Anti-Bacterial Agents,
pubmed-meshheading:17300931-Antifungal Agents,
pubmed-meshheading:17300931-Azides,
pubmed-meshheading:17300931-Chemistry,
pubmed-meshheading:17300931-Chemistry, Pharmaceutical,
pubmed-meshheading:17300931-Copper,
pubmed-meshheading:17300931-Drug Design,
pubmed-meshheading:17300931-Models, Chemical,
pubmed-meshheading:17300931-Molecular Conformation,
pubmed-meshheading:17300931-Raphanus
|
|
pubmed:year |
2007
|
|
pubmed:articleTitle |
Design and synthesis of beta-methoxyacrylate analogues via click chemistry and biological evaluations.
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|
pubmed:affiliation |
Plant Biotechnology Institute, National Research Council of Canada, 110 Gymnasium Place, Saskatoon, Sask., Canada S7N 0W9.
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|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
