Source:http://linkedlifedata.com/resource/pubmed/id/17297385
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
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pubmed:dateCreated |
2007-2-13
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pubmed:abstractText |
The association between cigarette smoking and the risk of colorectal cancer remains controversial. We examined this association using a population-based prospective cohort study in Miyagi, Japan. In 1990, we delivered a self-administered questionnaire on cigarette smoking and other health habits to 25 279 men who were 40-64 years of age and lived in 14 municipalities of Miyagi Prefecture. A total of 22 836 men responded (90.3% response rate). During 7 years of follow-up (158 376 person-years), we identified 188 patients of colorectal cancer. Relative risks and 95% confidence intervals were estimated by the Cox proportional-hazards regression analysis with adjustment for potential confounders. The multivariate-adjusted relative risks (95% confidence interval) of colorectal cancer for past smokers and current smokers compared with those who had never smoked were 1.73 (1.04-2.87) and 1.47 (0.93-2.34), respectively. Among current smokers, both a higher number of cigarettes smoked per day and an earlier age at which smoking had started were associated with a significant linear increase in risk (P for trend <0.05). Our findings are consistent with the hypothesis that cigarette smoking is associated with a higher risk of colorectal cancer in men.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0959-8278
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
16
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
102-7
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pubmed:meshHeading |
pubmed-meshheading:17297385-Adult,
pubmed-meshheading:17297385-Colorectal Neoplasms,
pubmed-meshheading:17297385-Humans,
pubmed-meshheading:17297385-Japan,
pubmed-meshheading:17297385-Male,
pubmed-meshheading:17297385-Middle Aged,
pubmed-meshheading:17297385-Prospective Studies,
pubmed-meshheading:17297385-Risk Factors,
pubmed-meshheading:17297385-Smoking
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pubmed:year |
2007
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pubmed:articleTitle |
Cigarette smoking and the risk of colorectal cancer among men: a prospective study in Japan.
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pubmed:affiliation |
Division of Epidemiology, Department of Public Health and Forensic Medicine, Tohoku University Graduate School of Medicine, Sendai, Japan. munira@mail.tains.tohoku.ac.jp
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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