| pubmed-article:1729687 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:1729687 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
| pubmed-article:1729687 | lifeskim:mentions | umls-concept:C0010802 | lld:lifeskim |
| pubmed-article:1729687 | lifeskim:mentions | umls-concept:C0206665 | lld:lifeskim |
| pubmed-article:1729687 | lifeskim:mentions | umls-concept:C1520195 | lld:lifeskim |
| pubmed-article:1729687 | lifeskim:mentions | umls-concept:C0175723 | lld:lifeskim |
| pubmed-article:1729687 | lifeskim:mentions | umls-concept:C1533164 | lld:lifeskim |
| pubmed-article:1729687 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:1729687 | pubmed:dateCreated | 1992-2-12 | lld:pubmed |
| pubmed-article:1729687 | pubmed:abstractText | A successful test is reported to generate long-range contiguous coverage of DNA from a human cytogenetic band in overlapping yeast artificial chromosomes (YACs). Seed YACs in band Xq26 were recovered from a targeted library of clones from Xq24-q28 with 14 probes, including probes for the hypoxanthine guanine phosphoribosyltransferase- and coagulation factor IX-encoding genes and nine probes used in linkage mapping. Neighboring YACs were then identified by 25 "walking" steps with end-clones, and the content of 71 probes in cognate YACs was verified by further hybridization analyses. The resultant contig extends across 8 million base pairs, including most of band Xq26, with an order of markers consistent with linkage data. YAC-based mapping, thus, permits steps toward a fully integrated physical and genetic map and is probably adequate to sustain most of the human genome project. | lld:pubmed |
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| pubmed-article:1729687 | pubmed:language | eng | lld:pubmed |
| pubmed-article:1729687 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1729687 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:1729687 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1729687 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:1729687 | pubmed:month | Jan | lld:pubmed |
| pubmed-article:1729687 | pubmed:issn | 0027-8424 | lld:pubmed |
| pubmed-article:1729687 | pubmed:author | pubmed-author:JohnsonSS | lld:pubmed |
| pubmed-article:1729687 | pubmed:author | pubmed-author:SchlessingerD... | lld:pubmed |
| pubmed-article:1729687 | pubmed:author | pubmed-author:D'UrsoMM | lld:pubmed |
| pubmed-article:1729687 | pubmed:author | pubmed-author:PiliaGG | lld:pubmed |
| pubmed-article:1729687 | pubmed:author | pubmed-author:LittleR DRD | lld:pubmed |
| pubmed-article:1729687 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:1729687 | pubmed:day | 1 | lld:pubmed |
| pubmed-article:1729687 | pubmed:volume | 89 | lld:pubmed |
| pubmed-article:1729687 | pubmed:geneSymbol | F9 | lld:pubmed |
| pubmed-article:1729687 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:1729687 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:1729687 | pubmed:pagination | 177-81 | lld:pubmed |
| pubmed-article:1729687 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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| pubmed-article:1729687 | pubmed:year | 1992 | lld:pubmed |
| pubmed-article:1729687 | pubmed:articleTitle | Yeast artificial chromosomes spanning 8 megabases and 10-15 centimorgans of human cytogenetic band Xq26. | lld:pubmed |
| pubmed-article:1729687 | pubmed:affiliation | Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO 63110. | lld:pubmed |
| pubmed-article:1729687 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:1729687 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:1729687 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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