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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2007-2-13
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pubmed:abstractText |
Interstitial cystitis is a painful bladder disease characterized by urgency, frequency and variable inflammation but there is no curative therapy. Suplatast tosilate (IPD-1151T) is an immunoregulatory compound that decreases interstitial cystitis symptoms but to our knowledge its mechanism of action is unknown. We investigated the effect of intravesical IPD-1151T on mediator release from bladder explants in experimental cystitis.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0022-5347
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
177
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1186-90
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pubmed:dateRevised |
2007-12-3
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pubmed:meshHeading |
pubmed-meshheading:17296442-Administration, Intravesical,
pubmed-meshheading:17296442-Animals,
pubmed-meshheading:17296442-Arylsulfonates,
pubmed-meshheading:17296442-Capillary Permeability,
pubmed-meshheading:17296442-Cell Culture Techniques,
pubmed-meshheading:17296442-Cystitis, Interstitial,
pubmed-meshheading:17296442-Female,
pubmed-meshheading:17296442-Histamine Antagonists,
pubmed-meshheading:17296442-Histamine Release,
pubmed-meshheading:17296442-Humans,
pubmed-meshheading:17296442-Male,
pubmed-meshheading:17296442-Mast Cells,
pubmed-meshheading:17296442-Mice,
pubmed-meshheading:17296442-Mice, Inbred C57BL,
pubmed-meshheading:17296442-Rats,
pubmed-meshheading:17296442-Rats, Sprague-Dawley,
pubmed-meshheading:17296442-Skin,
pubmed-meshheading:17296442-Sulfonium Compounds,
pubmed-meshheading:17296442-Tumor Necrosis Factor-alpha
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pubmed:year |
2007
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pubmed:articleTitle |
Intravesical suplatast tosilate (IPD-1151T) inhibits experimental bladder inflammation.
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pubmed:affiliation |
Department of Pharmacology and Experimental Therapeutics, Tufts University School of Medicine and Tufts-New England Medical Center, Boston, Massachusetts 02111, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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