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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2007-2-13
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pubmed:abstractText |
Phosphatidylethanol (PEth) is an aberrant phospholipid formed in vivo only in the presence of ethanol. In circulation PEth is associated with lipoproteins and is transferred from one lipoprotein to another. Lipoprotein-associated PEth affects endothelial and smooth muscle cells of blood vessels, but its effects on other cell types have not been explored. Adipocytes have a central role in metabolic syndrome and obesity. In this study we tested whether lipoprotein-associated PEth affects stearoyl-CoA desaturase 1 (SCD1) which plays a major role in lipid-mediated signaling in the differentiation of adipocytes.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0145-6008
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
31
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
376-82
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pubmed:dateRevised |
2009-11-19
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pubmed:meshHeading |
pubmed-meshheading:17295720-3T3 Cells,
pubmed-meshheading:17295720-Adipocytes,
pubmed-meshheading:17295720-Animals,
pubmed-meshheading:17295720-Cell Differentiation,
pubmed-meshheading:17295720-Gene Expression,
pubmed-meshheading:17295720-Glycerophospholipids,
pubmed-meshheading:17295720-Humans,
pubmed-meshheading:17295720-Lipid Metabolism,
pubmed-meshheading:17295720-Lipoproteins, HDL,
pubmed-meshheading:17295720-Mice,
pubmed-meshheading:17295720-RNA, Messenger,
pubmed-meshheading:17295720-Stearoyl-CoA Desaturase
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pubmed:year |
2007
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pubmed:articleTitle |
Effects of phosphatidylethanol on mouse adipocyte differentiation and expression of stearoyl-CoA desaturase 1.
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pubmed:affiliation |
Department of Internal Medicine, Clinical Research Center, University of Oulu, Oulu, Finland.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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