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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2007-8-3
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pubmed:abstractText |
The endothelial ADP receptor P2Y(1) is responsible for a large part of the reactive hyperemia following cardiac ischemia. Tissue plasminogen activator (t-PA) increases during reactive hyperemia. We postulated that the release of t-PA during reactive hyperemia could be mitigated through blocking the coronary endothelial P2Y(1) receptor.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0929-5305
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
24
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
115-22
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:17294140-Adenosine Diphosphate,
pubmed-meshheading:17294140-Angioplasty, Balloon, Coronary,
pubmed-meshheading:17294140-Animals,
pubmed-meshheading:17294140-Hyperemia,
pubmed-meshheading:17294140-Myocardial Ischemia,
pubmed-meshheading:17294140-Purinergic P2 Receptor Antagonists,
pubmed-meshheading:17294140-Receptors, Purinergic P2,
pubmed-meshheading:17294140-Receptors, Purinergic P2Y1,
pubmed-meshheading:17294140-Swine,
pubmed-meshheading:17294140-Thionucleotides,
pubmed-meshheading:17294140-Tissue Plasminogen Activator
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pubmed:year |
2007
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pubmed:articleTitle |
The ADP receptor P2Y(1) mediates t-PA release in pigs during cardiac ischemia.
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pubmed:affiliation |
Department of Cardiology, Lund University Hospital, Lund University, Lund 22185, Sweden.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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