Linked Life Data

17288166

Source:http://linkedlifedata.com/resource/pubmed/id/17288166

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
10
pubmed:dateCreated
2007-2-9
pubmed:abstractText
This research was stated on the group of infertile patient taking part in in vitro fertilization. The whole group of 60 random patients was divided into two subgroups: 10 persons smoking cigarettes and 50 nonsmokers. The number of follicles obtained after controlled ovarian hiperstimulation, the number of mature and immature oocytes and concentration of 17beta-estradiol in serum at the hCG day were measured for all women. There was also calculated the number of granulosa cells and the relative expression of the gene encoding FSHR. Comparing all testing groups, in smokers the worse ovarian answer for hiper-stimulation was observed. It was characterized by both the lower number of follicles and oocytes and also the lower concentration of estradiol in serum at hCG day. There was also observed lower number of granulosa cells in fluid from all folicles at diameter > 12 mm in smoking patients compared with nonsmokers. Analizing the relative expression of gene coding FSHR in granulosa cells significant differences between these two groups were demonstrated. The evaluation of the expression level showed its reduction in smokers (2). To compare it the average level of expression in nonsmokers was 24. Smoking cigarettes is correlated with the lower number of granulosa cells and the lower expression level of the gene coding for folitropin receptor.
pubmed:language
pol
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0033-2240
pubmed:author
pubmed:issnType
Print
pubmed:volume
63
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
834-7
pubmed:meshHeading
pubmed:year
2006
pubmed:articleTitle
[The expression of gene encoding folitropin receptor in granulosa cells in women smoking cigarettes and nonsmokers participating in vitro fertilization programme].
pubmed:affiliation
Klinika Niep?odno?ci i Endokrynologii Rozrodu, Katedry Ginekologii i Po?oznictwa, Akademii Medycznej w Poznaniu.
pubmed:publicationType
Journal Article, English Abstract