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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
1992-2-4
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pubmed:abstractText |
All patients with a diagnosis of cutaneous malignant melanoma (CMM) in Western Australia from 1980 to 1981 were observed for up to 6 years to determine vital status and to detect the development of local recurrences of the primary lesion. Approximately 35% of all patients had their tumors excised with surgical margins of less than 1 cm. When compared with patients whose tumors were excised with margins of at least 2 cm, the fatality rate in those with narrow margins was slightly less (rate ratio, 0.60; 95% confidence interval [CI], 0.20% to 1.80% for margins of 5 to 9 mm; rate ratio, 0.69; 95% CI, 0.26% to 1.87% for margins of 1 to 4 mm); however, this difference could have been caused by chance alone. The risk of local recurrence within 5 years after diagnosis was 2% (95% CI, 1% to 4%). The risk was strongly related to age and tumor thickness, but did not appear to be influenced by the width of excision (greater than 1 cm versus less than 1 cm: rate ratio, 1.03; 95% CI, 0.25% to 4.34%). The apparent lack of effect could be caused by to chance alone because the number of local recurrences was small.
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pubmed:commentsCorrections | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0008-543X
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pubmed:author | |
pubmed:issnType |
Print
|
pubmed:day |
15
|
pubmed:volume |
69
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
421-6
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:1728370-Adult,
pubmed-meshheading:1728370-Aged,
pubmed-meshheading:1728370-Aged, 80 and over,
pubmed-meshheading:1728370-Female,
pubmed-meshheading:1728370-Humans,
pubmed-meshheading:1728370-Male,
pubmed-meshheading:1728370-Melanoma,
pubmed-meshheading:1728370-Middle Aged,
pubmed-meshheading:1728370-Neoplasm Recurrence, Local,
pubmed-meshheading:1728370-Skin Neoplasms,
pubmed-meshheading:1728370-Survival Analysis,
pubmed-meshheading:1728370-Treatment Outcome
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pubmed:year |
1992
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pubmed:articleTitle |
The effects of surgical treatment on survival and local recurrence of cutaneous malignant melanoma.
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pubmed:affiliation |
Department of Pathology, University of Western Australia, Nedlands.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|