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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2007-2-6
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pubmed:abstractText |
Obsessive-compulsive disorder (OCD) is a debilitating familial psychiatric illness with associated brain abnormalities in the white matter. The gene for oligodendrocyte lineage transcription factor 2 (OLIG2) is an essential regulator in the development of cells that produce white matter (myelin). The OLIG2 gene is also highly expressed in brain regions implicated in OCD.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0003-990X
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pubmed:author |
pubmed-author:BirnsJulieJ,
pubmed-author:ChabaneNadiaN,
pubmed-author:DelormeRichardR,
pubmed-author:FagernessJesenJ,
pubmed-author:JenikeEricE,
pubmed-author:JenikeMichael AMA,
pubmed-author:LeboyerMarionM,
pubmed-author:PaulsDavid LDL,
pubmed-author:PerlisRoyR,
pubmed-author:PlatkoJillJ,
pubmed-author:RauchScott LSL,
pubmed-author:SmollerJordan WJW,
pubmed-author:StewartS EvelynSE
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pubmed:issnType |
Print
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pubmed:volume |
64
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
209-14
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pubmed:dateRevised |
2007-12-3
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pubmed:meshHeading |
pubmed-meshheading:17283288-Basic Helix-Loop-Helix Transcription Factors,
pubmed-meshheading:17283288-Chromosome Mapping,
pubmed-meshheading:17283288-Comorbidity,
pubmed-meshheading:17283288-Family,
pubmed-meshheading:17283288-Gene Frequency,
pubmed-meshheading:17283288-Genetic Markers,
pubmed-meshheading:17283288-Genetic Predisposition to Disease,
pubmed-meshheading:17283288-Haplotypes,
pubmed-meshheading:17283288-Humans,
pubmed-meshheading:17283288-Linkage Disequilibrium,
pubmed-meshheading:17283288-Nerve Tissue Proteins,
pubmed-meshheading:17283288-Obsessive-Compulsive Disorder,
pubmed-meshheading:17283288-Pedigree,
pubmed-meshheading:17283288-Phenotype,
pubmed-meshheading:17283288-Polymorphism, Single Nucleotide,
pubmed-meshheading:17283288-Tourette Syndrome
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pubmed:year |
2007
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pubmed:articleTitle |
A genetic family-based association study of OLIG2 in obsessive-compulsive disorder.
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pubmed:affiliation |
Psychiatric Neuroscience Research Division, and Obsessive-Compulsive Disorder Clinic, Harvard Medical School, Massachusetts General Hospital, Boston, MA 02114, USA.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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