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rdf:type |
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lifeskim:mentions |
umls-concept:C0001675,
umls-concept:C0001737,
umls-concept:C0006409,
umls-concept:C0032150,
umls-concept:C0036043,
umls-concept:C0086582,
umls-concept:C0205148,
umls-concept:C0206255,
umls-concept:C0444659,
umls-concept:C0597551,
umls-concept:C1705493
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pubmed:issue |
14
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pubmed:dateCreated |
2007-3-19
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pubmed:abstractText |
The merozoite surface protein-3 long synthetic peptide (MSP3-LSP) comprises the amino acid sequence 186-276 of the Plasmodium falciparum protein MSP3. It is currently in development as an erythrocytic stage (blood stage) malaria vaccine candidate. We report here the first data on the safety, reactogenicity and immunogenicity of three doses of MSP3-LSP, adjuvanted with aluminium hydroxide, in healthy male adults living in a malaria endemic area.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0264-410X
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pubmed:author |
pubmed-author:CousensSimonS,
pubmed-author:Cuzzin-OuattaraNadineN,
pubmed-author:DerméAssetou IAI,
pubmed-author:DiarraAmidouA,
pubmed-author:GansanéAdamaA,
pubmed-author:KonatéAmadou TAT,
pubmed-author:LeroyOdileO,
pubmed-author:NébiéIssaI,
pubmed-author:OuédraogoAlphonseA,
pubmed-author:OuédraogoAmidouA,
pubmed-author:SirimaSodiomon BSB,
pubmed-author:SoulamaIssiakaI,
pubmed-author:TionoAlfred BAB
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pubmed:issnType |
Print
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pubmed:day |
30
|
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pubmed:volume |
25
|
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2723-32
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:17280744-Adult,
pubmed-meshheading:17280744-Amino Acid Sequence,
pubmed-meshheading:17280744-Antigens, Protozoan,
pubmed-meshheading:17280744-Humans,
pubmed-meshheading:17280744-Interferon-gamma,
pubmed-meshheading:17280744-Lymphocyte Activation,
pubmed-meshheading:17280744-Malaria Vaccines,
pubmed-meshheading:17280744-Male,
pubmed-meshheading:17280744-Molecular Sequence Data,
pubmed-meshheading:17280744-Peptide Fragments,
pubmed-meshheading:17280744-Safety,
pubmed-meshheading:17280744-Single-Blind Method,
pubmed-meshheading:17280744-Vaccines, Synthetic
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pubmed:year |
2007
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pubmed:articleTitle |
Safety and immunogenicity of the Plasmodium falciparum merozoite surface protein-3 long synthetic peptide (MSP3-LSP) malaria vaccine in healthy, semi-immune adult males in Burkina Faso, West Africa.
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pubmed:affiliation |
Centre National de Recherche et de Formation sur le Paludisme (CNRFP), 01 BP 2208 Ouagadougou 01, Burkina Faso. s.sirima.cnlp@fasonet.bf
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pubmed:publicationType |
Journal Article,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't
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