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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2007-4-20
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pubmed:abstractText |
We evaluated the association between the VDR translation start site polymorphism and osteoporotic phenotypes among 6698 older white women. Women with the C/C genotype had lower wrist BMD and an increased risk of wrist and all non-spine/low-trauma fractures. The high frequency of this variant confers a population attributable risk that is similar to several established risk factors for fracture.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0884-0431
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pubmed:author |
pubmed-author:CauleyJane AJA,
pubmed-author:CayabyabSheliaS,
pubmed-author:CummingsSteven RSR,
pubmed-author:EnsrudKristine EKE,
pubmed-author:HillierTeresa ATA,
pubmed-author:HochbergMarc CMC,
pubmed-author:LeeJocelyn MJM,
pubmed-author:MoffettSusan PSP,
pubmed-author:OsL OLO,
pubmed-author:PeltzGaryG,
pubmed-author:ZmudaJoseph MJM
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pubmed:issnType |
Print
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pubmed:volume |
22
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
730-6
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:17280526-Age Factors,
pubmed-meshheading:17280526-Aged,
pubmed-meshheading:17280526-Amino Acid Sequence,
pubmed-meshheading:17280526-Bone Density,
pubmed-meshheading:17280526-Codon, Initiator,
pubmed-meshheading:17280526-European Continental Ancestry Group,
pubmed-meshheading:17280526-Female,
pubmed-meshheading:17280526-Fractures, Bone,
pubmed-meshheading:17280526-Gene Frequency,
pubmed-meshheading:17280526-Genotype,
pubmed-meshheading:17280526-Humans,
pubmed-meshheading:17280526-Models, Genetic,
pubmed-meshheading:17280526-Polymorphism, Single Nucleotide,
pubmed-meshheading:17280526-Prospective Studies,
pubmed-meshheading:17280526-Receptors, Calcitriol,
pubmed-meshheading:17280526-Risk Factors
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pubmed:year |
2007
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pubmed:articleTitle |
Association of the VDR translation start site polymorphism and fracture risk in older women.
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pubmed:affiliation |
Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261, USA. susan.moffett@hgen.pitt.edu
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, N.I.H., Extramural
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