Source:http://linkedlifedata.com/resource/pubmed/id/17276746
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
2007-2-5
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pubmed:abstractText |
Many chromosomal regions for susceptibility to autism spectrum disorders (ASDs) have been identified, but few have reached genomewide significance. In response, researchers have attempted to increase the power of their analyses by stratifying samples to increase phenotypic homogeneity. Although homogeneity has typically been defined by a single variable, resultant groups often differ in other dimensions that may be directly pertinent. Group differences in age, gender, IQ, and measures of autism severity are examined as related to Autism Diagnostic Interview-Revised (ADI-R) domains previously used for subsetting or Quantitative Trait Analysis (QTL).
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0006-3223
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
61
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
438-48
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pubmed:dateRevised |
2011-2-23
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pubmed:meshHeading |
pubmed-meshheading:17276746-Adolescent,
pubmed-meshheading:17276746-Adult,
pubmed-meshheading:17276746-Age Factors,
pubmed-meshheading:17276746-Autistic Disorder,
pubmed-meshheading:17276746-Biomedical Research,
pubmed-meshheading:17276746-Child,
pubmed-meshheading:17276746-Child, Preschool,
pubmed-meshheading:17276746-Female,
pubmed-meshheading:17276746-Humans,
pubmed-meshheading:17276746-Interview, Psychological,
pubmed-meshheading:17276746-Language,
pubmed-meshheading:17276746-Male,
pubmed-meshheading:17276746-Middle Aged,
pubmed-meshheading:17276746-Phenotype,
pubmed-meshheading:17276746-Severity of Illness Index,
pubmed-meshheading:17276746-Sex Factors
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pubmed:year |
2007
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pubmed:articleTitle |
Using the autism diagnostic interview--revised to increase phenotypic homogeneity in genetic studies of autism.
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pubmed:affiliation |
University of Michigan Autism and Communication Disorders Center, Ann Arbor, Michigan, USA.
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pubmed:publicationType |
Journal Article,
Research Support, N.I.H., Extramural
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