Linked Life Data

17274465

Source:http://linkedlifedata.com/resource/pubmed/id/17274465

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2007-2-5
pubmed:abstractText
Ischemic heart disease has a complex etiology apparently involving gene polymorphisms in the renin-angiotensin system. I/D ACE, A11166C AT1R and C677T MTHFR polymorphisms seem to be associated with a higher risk of myocardial infarction. The aim of this study was to establish the distribution of ACE, AT1R and MTHFR genotypes, and search for correlations with left ventricular anatomic measurements in Polish patients with a history of myocardial infarction. INVESTIGATED GROUP AND METHOD: Our study group comprised 100 patients (14 females and 86 males, aged 54.2 +/- 9.2 years) and 100 age-matched controls (10 females and 90 males, aged 52.3 +/- 10.0 years). We used PCR and PRC-RFLP to detect ACE I/D, AT1RAl 166C and MTHFR C677T gene polymorphisms, respectively.
pubmed:language
pol
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0032-3772
pubmed:author
pubmed:issnType
Print
pubmed:volume
115
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
105-11
pubmed:dateRevised
2010-4-1
pubmed:meshHeading
pubmed:year
2006
pubmed:articleTitle
[Allelic variants of genes: angiotensin I-converting enzyme (ACE), angiotensin-II type 1 receptor (AT1R), methylenetetrahydrofolate reductase and left ventricular mass in patients with myocardial infarction].
pubmed:affiliation
Katedra Diagnostyki Laboratoryjnej.
pubmed:publicationType
Journal Article, English Abstract