17272778

Source:http://linkedlifedata.com/resource/pubmed/id/17272778

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0005854, umls-concept:C0020456, umls-concept:C0034693, umls-concept:C0035124, umls-concept:C0080103, umls-concept:C0165519, umls-concept:C0205234, umls-concept:C0242606, umls-concept:C0277785, umls-concept:C0917798, umls-concept:C1879547
pubmed:issue	3
pubmed:dateCreated	2007-2-27
pubmed:abstractText	Hyperglycemia is linked to a worse outcome after ischemic stroke. Among the manifestations of brain damage caused by ischemia are blood-brain barrier (BBB) disruption and edema formation. Oxidative stress and matrix metalloproteinase-9 (MMP-9) activation are implicated in BBB dysfunction after ischemia/reperfusion injury. Our present study was designed to clarify the relation among hyperglycemia, oxidative stress, and MMP-9 activation associated with BBB dysfunction after transient focal cerebral ischemia (tFCI).
pubmed:grant	http://linkedlifedata.com/resource/pubmed/grant/P50 NS014543-27, http://linkedlifedata.com/resource/pubmed/grant/P50NS14543, http://linkedlifedata.com/resource/pubmed/grant/R01 NS025372-19, http://linkedlifedata.com/resource/pubmed/grant/R01 NS036147-10, http://linkedlifedata.com/resource/pubmed/grant/R01 NS038653-09, http://linkedlifedata.com/resource/pubmed/grant/R01 NS25372, http://linkedlifedata.com/resource/pubmed/grant/R01 NS36147, http://linkedlifedata.com/resource/pubmed/grant/R01 NS38653
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pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/0235266
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Matrix Metalloproteinase 9, http://linkedlifedata.com/resource/pubmed/chemical/Superoxide Dismutase, http://linkedlifedata.com/resource/pubmed/chemical/superoxide dismutase 1
pubmed:status	MEDLINE
pubmed:month	Mar
pubmed:issn	1524-4628
pubmed:author	pubmed-author:ChanPak HPH, pubmed-author:KamadaHiroshiH, pubmed-author:NitoChikakoC, pubmed-author:YuFengshanF
pubmed:issnType	Electronic
pubmed:volume	38
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	1044-9
pubmed:dateRevised	2010-9-20
pubmed:meshHeading	pubmed-meshheading:17272778-Animals, pubmed-meshheading:17272778-Animals, Genetically Modified, pubmed-meshheading:17272778-Blood-Brain Barrier, pubmed-meshheading:17272778-Brain Ischemia, pubmed-meshheading:17272778-Enzyme Activation, pubmed-meshheading:17272778-Humans, pubmed-meshheading:17272778-Hyperglycemia, pubmed-meshheading:17272778-Male, pubmed-meshheading:17272778-Matrix Metalloproteinase 9, pubmed-meshheading:17272778-Oxidative Stress, pubmed-meshheading:17272778-Rats, pubmed-meshheading:17272778-Rats, Sprague-Dawley, pubmed-meshheading:17272778-Reperfusion Injury, pubmed-meshheading:17272778-Superoxide Dismutase
pubmed:year	2007
pubmed:articleTitle	Influence of hyperglycemia on oxidative stress and matrix metalloproteinase-9 activation after focal cerebral ischemia/reperfusion in rats: relation to blood-brain barrier dysfunction.
pubmed:affiliation	Department of Neurosurgery, Stanford University, Stanford, CA 94305-5487, USA.
pubmed:publicationType	Journal Article, Comparative Study, Research Support, N.I.H., Extramural