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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2007-2-27
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pubmed:abstractText |
Platelet-activating factor (PAF) and oxidized unsaturated free fatty acids have been postulated to aggravate neuronal damage in the postischemic brain. Type II PAF-acetylhydrolase (PAF-AH II) not only terminates signals by PAF by its PAF-hydrolyzing activity but also protects cells against oxidative stress. We examined whether PAF-AH II can rescue cerebral neurons against ischemic insults.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
1524-4628
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pubmed:author |
pubmed-author:AokiJunkenJ,
pubmed-author:AraiHiroyukiH,
pubmed-author:EndoShunroS,
pubmed-author:HamadaHideoH,
pubmed-author:HayashiNakamasaN,
pubmed-author:HiragaKoichiK,
pubmed-author:HirashimaYutakaY,
pubmed-author:InoueTakaoT,
pubmed-author:IshiiYokoY,
pubmed-author:KatoIchiroI,
pubmed-author:KinouchiHiroyukiH,
pubmed-author:KonoNozomuN,
pubmed-author:OdaMasayaM,
pubmed-author:OyaTakeshiT,
pubmed-author:UmemuraKimikoK
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pubmed:issnType |
Electronic
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pubmed:volume |
38
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1063-8
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pubmed:meshHeading |
pubmed-meshheading:17272759-1-Alkyl-2-acetylglycerophosphocholine Esterase,
pubmed-meshheading:17272759-Animals,
pubmed-meshheading:17272759-Brain Ischemia,
pubmed-meshheading:17272759-Disease Models, Animal,
pubmed-meshheading:17272759-Female,
pubmed-meshheading:17272759-Humans,
pubmed-meshheading:17272759-Male,
pubmed-meshheading:17272759-Mice,
pubmed-meshheading:17272759-Mice, Inbred C57BL,
pubmed-meshheading:17272759-Mice, Transgenic,
pubmed-meshheading:17272759-Neuroprotective Agents
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pubmed:year |
2007
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pubmed:articleTitle |
Neuroprotective role of transgenic PAF-acetylhydrolase II in mouse models of focal cerebral ischemia.
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pubmed:affiliation |
Department of Neurosurgery, University of Toyama Faculty of Medicine, Toyama, Japan.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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