Source:http://linkedlifedata.com/resource/pubmed/id/17271649
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rdf:type | |
lifeskim:mentions | |
pubmed:dateCreated |
2007-2-2
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pubmed:abstractText |
Current peak detections algorithms for processing mass spectrometry (MS) spectra generally rely on two dimensional techniques for identifying the location and intensity of peaks from a single spectrum. However, when high performance liquid chromatography (HPLC) is coupled with mass spectrometry, a third dimension, retention time, is introduced. The ensemble of MS spectra may then be regarded as a 3D surface where spectral intensity is a function of m/z (mass-to-charge) and time. This suggests that peak localization can be improved by incorporating the time domain data and average data across both dimensions. This work describes a surface intensity analysis algorithm and the results of its use.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:status |
PubMed-not-MEDLINE
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pubmed:issn |
1557-170X
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
1
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
220-3
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pubmed:year |
2004
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pubmed:articleTitle |
Surface analysis of peptide mass spectra to improve time and mass localization.
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pubmed:affiliation |
Dept. of Biomedical Eng., McGill Univ., Que., Canada.
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pubmed:publicationType |
Journal Article
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