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PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2007-2-2
pubmed:abstractText
Current peak detections algorithms for processing mass spectrometry (MS) spectra generally rely on two dimensional techniques for identifying the location and intensity of peaks from a single spectrum. However, when high performance liquid chromatography (HPLC) is coupled with mass spectrometry, a third dimension, retention time, is introduced. The ensemble of MS spectra may then be regarded as a 3D surface where spectral intensity is a function of m/z (mass-to-charge) and time. This suggests that peak localization can be improved by incorporating the time domain data and average data across both dimensions. This work describes a surface intensity analysis algorithm and the results of its use.
pubmed:language
eng
pubmed:journal
pubmed:status
PubMed-not-MEDLINE
pubmed:issn
1557-170X
pubmed:author
pubmed:issnType
Print
pubmed:volume
1
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
220-3
pubmed:year
2004
pubmed:articleTitle
Surface analysis of peptide mass spectra to improve time and mass localization.
pubmed:affiliation
Dept. of Biomedical Eng., McGill Univ., Que., Canada.
pubmed:publicationType
Journal Article