Linked Life Data

1726647

Source:http://linkedlifedata.com/resource/pubmed/id/1726647

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
1992-9-23
pubmed:abstractText
The value of magnetic resonance (MR) imaging, with two-dimensional (2D) spin-echo and FISP (fast imaging with steady-state precession) and FLASH (fast low-angle shot) three-dimensional (3D) gradient-echo sequences, for the detection of hyaline cartilage defects of the femoral condyle and the tibial plateau, was investigated in an animal model. In eight dogs, the anterior cruciate ligament was transected in one knee joint, resulting in rapid development of osteoarthritis with degeneration of the hyaline cartilage. At autopsy, 24 cartilage lesions were found, which were classified into four grades. The overall detection of cartilage lesions with MR imaging was poor. Only five of the 24 lesions were visible on 2D spin-echo images, while 11 of 24 were visible on 3D FISP images and 15 of 24 were seen on 3D FLASH images. The best results were obtained in advanced stages of cartilage degeneration, involving ulceration and complete abrasion of the cartilage layer. Signal loss or signal intensity increase in the cartilage layer was seen inconsistently in grades 3 and 4 degeneration. In this animal model, 2D spin-echo imaging was inadequate for the diagnosis of hyaline cartilage lesions, while 3D gradient-echo imaging permitted satisfactory diagnosis in only grade 4 cartilage disease.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:issn
1053-1807
pubmed:author
pubmed:issnType
Print
pubmed:volume
1
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
665-72
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:articleTitle
Experimental hyaline cartilage lesions: two-dimensional spin-echo versus three-dimensional gradient-echo MR imaging.
pubmed:affiliation
Department of Diagnostic Radiology, University of Technology, Aaachen, Germany.
pubmed:publicationType
Journal Article, Comparative Study