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pubmed-article:17265479pubmed:abstractTextAngiotensin II (Ang II) is known to have proinflammatory actions, and Ang II type 1 (AT(1)) receptors are up-regulated in the rheumatoid synovium, suggesting that this receptor could be a therapeutic target. The purpose of this study was to investigate the antiinflammatory potential of the selective AT(1) receptor antagonist losartan, which is currently used for the treatment of cardiovascular disease.lld:pubmed
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pubmed-article:17265479pubmed:articleTitleAngiotensin II type 1 receptor as a novel therapeutic target in rheumatoid arthritis: in vivo analyses in rodent models of arthritis and ex vivo analyses in human inflammatory synovitis.lld:pubmed
pubmed-article:17265479pubmed:affiliationUniversity of Paisley, Paisley, UK.lld:pubmed
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