Linked Life Data

17262826

Source:http://linkedlifedata.com/resource/pubmed/id/17262826

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2007-5-17
pubmed:abstractText
Changes in gene expression affect the energy budget of a cell. A previous contribution estimated the energetic cost of yeast mRNA and protein expression from very limited information on protein half-lives. Using recently published genome-scale measurements of protein half-lives, I here confirm that even small increases in gene expression are opposed by natural selection. In small organisms with large effective population sizes, the evolution of transcription and translation rates are thus not evolutionarily neutral processes.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
1552-5007
pubmed:author
pubmed:copyrightInfo
(c) 2007 Wiley-Liss, Inc.
pubmed:issnType
Print
pubmed:day
15
pubmed:volume
308
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
322-4
pubmed:dateRevised
2009-11-19
pubmed:meshHeading
pubmed:year
2007
pubmed:articleTitle
Energy costs constrain the evolution of gene expression.
pubmed:affiliation
Department of Biochemistry, University of Zurich, Winterthurerstrasse 190, CH-8057 Zurich, Switzerland. aw@bioc.unizh.ch
pubmed:publicationType
Journal Article, Comparative Study