rdf:type |
|
lifeskim:mentions |
umls-concept:C0003011,
umls-concept:C0017262,
umls-concept:C0018787,
umls-concept:C0022116,
umls-concept:C0025914,
umls-concept:C0026809,
umls-concept:C0185117,
umls-concept:C0205191,
umls-concept:C0205217,
umls-concept:C0205263,
umls-concept:C0332206,
umls-concept:C2911684
|
pubmed:issue |
1
|
pubmed:dateCreated |
2007-1-30
|
pubmed:abstractText |
This study was performed to investigate the role of chronic pretreatment with angiotensin II type 1 receptor antagonists (ARB) and angiotensin converting enzyme inhibitors (ACE-I) in myocardial infarction (MI) and ischemic preconditioning (iPC). Little is known about molecular mechanisms of MI and iPC, especially about protein kinase C (PKC) isozyme levels induced by chronic pharmacologic pretreatment with ARB and ACE-I. To address one of the most important signal molecules in iPC, the PKC system was investigated in an ischemia/reperfusion model using isolated mouse hearts.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Jan
|
pubmed:issn |
0160-2446
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
49
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
46-55
|
pubmed:dateRevised |
2010-11-18
|
pubmed:meshHeading |
pubmed-meshheading:17261963-Angiotensin II Type 1 Receptor Blockers,
pubmed-meshheading:17261963-Angiotensin Receptor Antagonists,
pubmed-meshheading:17261963-Angiotensin-Converting Enzyme Inhibitors,
pubmed-meshheading:17261963-Animals,
pubmed-meshheading:17261963-Benzimidazoles,
pubmed-meshheading:17261963-Biphenyl Compounds,
pubmed-meshheading:17261963-Heart,
pubmed-meshheading:17261963-Male,
pubmed-meshheading:17261963-Mice,
pubmed-meshheading:17261963-Mice, Inbred C57BL,
pubmed-meshheading:17261963-Myocardial Infarction,
pubmed-meshheading:17261963-Myocardial Ischemia,
pubmed-meshheading:17261963-Myocardium,
pubmed-meshheading:17261963-Protein Kinase C-epsilon,
pubmed-meshheading:17261963-Ramipril,
pubmed-meshheading:17261963-Tetrazoles,
pubmed-meshheading:17261963-Time Factors
|
pubmed:year |
2007
|
pubmed:articleTitle |
Chronic angiotensin II receptor blockade induces cardioprotection during ischemia by increased PKC-epsilon expression in the mouse heart.
|
pubmed:affiliation |
Department of Internal Medicine and Cardiology, Dresden University of Technology, Dresden, Germany. StefanALange@t-online.de
|
pubmed:publicationType |
Journal Article,
Comparative Study
|