Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2007-3-30
pubmed:abstractText
The sites of action of inhalant drugs are not completely known but recent studies suggest that ion channels that regulate neuronal excitability may be particularly sensitive. Lamotrigine, a newer anticonvulsant, has a modulating effect on excitatory amino acid-glutamate. We describe the use of lamotrigine in the treatment of a patient with inhalant dependence. A 21-year-old male with no history of other substance problems complained of problems with exacerbating use of inhalants for 4 years. He received a course of individual and behavior psychotherapy for 2 months. However, the psychotherapy was not effective. He then was treated with lamotrigine 100 mg per day. He has been on the dose of this medication for more than 6 months and stopped the use of inhalants. Experience with our patient suggests that lamotrigine might be effective in treating inhalant dependence. Further controlled studies are required to confirm its efficacy in patients of this type.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0278-5846
pubmed:author
pubmed:issnType
Print
pubmed:day
13
pubmed:volume
31
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
769-71
pubmed:meshHeading
pubmed:year
2007
pubmed:articleTitle
Treatment of inhalant dependence with lamotrigine.
pubmed:affiliation
Department of Psychiatry, Tzu-Chi General Hospital, Hualien City, Taiwan, ROC. shengmp@so-net.net.tw
pubmed:publicationType
Journal Article, Case Reports