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rdf:type | |
lifeskim:mentions | |
pubmed:dateCreated |
1992-5-12
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pubmed:abstractText |
We measured plasma endothelin-1-like immunoreactivity (ET-1-LI) levels in the peripheral vein of 70 healthy children (37 males and 33 females) aged 5 days to 15 years to establish the normal range in children, and compared them with those in 11 normal adults (age, mean +/- SD; 29.5 +/- 5.7 years, 6 males and 5 females). Plasma ET-1-LI levels (pg/ml, mean +/- SD) in children of each age group and adults were as follows: children younger than 1 month = 23.4 +/- 3.9 (n = 10), 1-3 months = 25.0 +/- 6.1 (n = 8), 3-6 months = 17.0 +/- 1.4 (n = 8), 6 months to 1 year = 14.0 +/- 1.7 (n = 13), 1-5 years = 13.8 +/- 2.6 (n = 11), 5-10 years = 13.6 +/- 1.6 (n = 10), 10-15 years = 12.9 +/- 2.2 (n = 10), and adults = 13.2 +/- 2.4 (n = 11). There was no significant difference in plasma ET-1-LI levels between males and females in each age group. Plasma ET-1-LI levels in children younger than 3 months were significantly (p less than 0.01) higher than those in older children or adults. After 3 months of age, plasma ET-1-LI levels were nearly constant at all ages. This is the first report to establish the normal range of plasma ET-1-LI levels in children.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0160-2446
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
17 Suppl 7
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
S404-5
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:1725392-Adolescent,
pubmed-meshheading:1725392-Adult,
pubmed-meshheading:1725392-Aging,
pubmed-meshheading:1725392-Child,
pubmed-meshheading:1725392-Child, Preschool,
pubmed-meshheading:1725392-Endothelins,
pubmed-meshheading:1725392-Female,
pubmed-meshheading:1725392-Humans,
pubmed-meshheading:1725392-Infant,
pubmed-meshheading:1725392-Infant, Newborn,
pubmed-meshheading:1725392-Male,
pubmed-meshheading:1725392-Reference Values
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pubmed:year |
1991
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pubmed:articleTitle |
Plasma endothelin levels in healthy children: high values in early infancy.
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pubmed:affiliation |
Department of Pediatrics, Kyoto University School of Medicine, Japan.
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pubmed:publicationType |
Journal Article
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