Linked Life Data

17248595

Source:http://linkedlifedata.com/resource/pubmed/id/17248595

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2010-6-28
pubmed:abstractText
Sporulating cells of Saccharomyces cerevisiae show an increasing sensitivity to ultraviolet irradiation. Maximum sensitivity is reached at a time comparable to meiotic prophase. Sensitivity is expressed as reduced sporulation after the irradiation. The uv effect can be efficiently reversed by photoreactivating light. Viability is also more severely affected during premeiotic DNA synthesis and during meiosis than in earlier stages in sporulation. Cells left in sporulation medium after the irradiation show a reduced viability compared with the cells plated immediately after the irradiation. Non-sporulating diploids do not acquire sensitivity when exposed to sporulation medium, hence the sensitivity is related to the sporulation process. That meiosis itself is affected, rather than spore formation alone, is evident from experiments in which the uv irradiation interferes with the uncovering of a recessive marker and with commitment to meiosis. It is proposed that during meiotic prophase, the DNA repair system is different from that found in vegetative cells.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:status
PubMed-not-MEDLINE
pubmed:month
Apr
pubmed:issn
0016-6731
pubmed:author
pubmed:issnType
Print
pubmed:volume
73
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
531-41
pubmed:dateRevised
2010-9-15
pubmed:year
1973
pubmed:articleTitle
Sensitivity of meiotic yeast cells to ultraviolet light.
pubmed:affiliation
Department of Genetics, University of Washington, Seattle, Washington 98195.
pubmed:publicationType
Journal Article