Linked Life Data

17246108

Source:http://linkedlifedata.com/resource/pubmed/id/17246108

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2010-6-28
pubmed:abstractText
The frequencies of newly induced male-sterilizing lesions on both the X and Y chromosomes of Drosophila melanogaster were determined after either 4000 r of gamma-irradiation or adult feeding of ethyl methanesulfonate. The Y chromosome is approximately twice as sensitive as the X chromosome to newly induced male-sterilizing lesions after gamma-irradiation, but slightly less sensitive after ethyl methanesulfonate treatment. A large proportion of the radiation-induced lesions are associated with Y-autosome or X-autosome translocations, with the Y chromosome recovered in translocations far in excess of the frequency expected from metaphase lengths. Although translocations between the X and Y chromosomes or between autosomes do not appear to sterilize heterozygous males, interchanges between sex chromosomes and autosomes often sterilize males carrying them in a dominant manner, suggesting that the organization of the genome is critical for normal spermatogenesis. Complementation tests between recessive Y-linked male-sterilizing mutants do not reveal the existence of any additional fertility loci beyond the six previously defined.
pubmed:commentsCorrections
pubmed:language
eng
pubmed:journal
pubmed:status
PubMed-not-MEDLINE
pubmed:month
Feb
pubmed:issn
0016-6731
pubmed:author
pubmed:issnType
Print
pubmed:volume
103
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
219-34
pubmed:dateRevised
2010-9-15
pubmed:year
1983
pubmed:articleTitle
Analysis of Y-Linked Mutations to Male Sterility in DROSOPHILA MELANOGASTER.
pubmed:affiliation
Department of Biology, B-022, University of California, San Diego, La Jolla, California 92093.
pubmed:publicationType
Journal Article