Linked Life Data

1724608

Source:http://linkedlifedata.com/resource/pubmed/id/1724608

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1992-4-16
pubmed:abstractText
A role for antigen-binding B cells in the induction of antigen-dependent B cells producing antigen-nonspecific immunoglobulins (nIFC) is analyzed. An in vitro immune response system was used; sheep red blood cells were employed as the antigen. It is shown that cocultivation of antigen-binding B cells with resting naive splenocytes in the presence of homologous antigen resulted not only in an increase in the number of antibody-forming cells (AFC), but also in a sharp increase in nIFC. Cocultivation of G0 splenocytes with primed B cells depleted for antigen-binding cells did not affect AFC induction, and only slightly augmented the number of nIFC. It is suggested that some of the nIFC appearing after antigenic stimulation arise from resting B lymphocytes in response (direct or indirect) to nonspecific B-cell factor(s).
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0955-9701
pubmed:author
pubmed:issnType
Print
pubmed:volume
2
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
361-6
pubmed:dateRevised
2011-11-17
pubmed:meshHeading
pubmed:year
1991
pubmed:articleTitle
Role of antigen-binding B lymphocytes in the formation of antigen-dependent nonspecific immunoglobulin-forming cells.
pubmed:affiliation
Institute of Viral Preparations, Academy of Medical Sciences of the USSR, Moscow.
pubmed:publicationType
Journal Article