Source:http://linkedlifedata.com/resource/pubmed/id/17244651
Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
Pt 4
|
pubmed:dateCreated |
2007-2-8
|
pubmed:databankReference |
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/AY650052,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/AY650054,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/AY857765,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/DQ167190,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/DQ167191,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/DQ167192,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/DQ167193
|
pubmed:abstractText |
Iron (Fe) is a ubiquitous redox-active element essential for most life. The formation of localized cell wall appositions, the oxidative burst and the production of pathogenesis-related proteins are hallmarks of plant defense responses. Here, we report that iron is a central mediator linking these three phenomena. We show that in response to pathogen attack, reactive Fe3+, but not Fe2+, is deposited at cell wall appositions where it accumulates and mediates the oxidative burst. We provide evidence that the bulk secretion of Fe3+ provoked by pathogen attack leads to intracellular iron depletion, and that H2O2 itself induces ATP-dependent intracellular iron efflux. Finally, we demonstrate that this intracellular iron depletion promotes the transcription of pathogenesis-related genes in concert with H2O2. This work identifies iron as an underlying factor associated with the oxidative burst and regulating cereal defenses, and establishes links between disease-related iron homeostasis in plants and animals.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Feb
|
pubmed:issn |
0021-9533
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:day |
15
|
pubmed:volume |
120
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
596-605
|
pubmed:dateRevised |
2008-11-21
|
pubmed:meshHeading |
pubmed-meshheading:17244651-Ascomycota,
pubmed-meshheading:17244651-Gene Expression,
pubmed-meshheading:17244651-Homeostasis,
pubmed-meshheading:17244651-Hydrogen Peroxide,
pubmed-meshheading:17244651-Iron,
pubmed-meshheading:17244651-Iron Overload,
pubmed-meshheading:17244651-Models, Biological,
pubmed-meshheading:17244651-Molecular Sequence Data,
pubmed-meshheading:17244651-Plant Leaves,
pubmed-meshheading:17244651-Plant Physiological Phenomena,
pubmed-meshheading:17244651-Reactive Oxygen Species,
pubmed-meshheading:17244651-Triticum
|
pubmed:year |
2007
|
pubmed:articleTitle |
Targeted alterations in iron homeostasis underlie plant defense responses.
|
pubmed:affiliation |
Department of Biology, University of Saskatchewan, 112 Science Place, Saskatoon, SK S7N 5E2, Canada.
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|