Source:http://linkedlifedata.com/resource/pubmed/id/17237065
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
2007-3-22
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pubmed:abstractText |
Due to the large number of peaks in mass spectra of low-molecular-weight (LMW) enriched sera, a systematic method is needed to select a parsimonious set of peaks to facilitate biomarker identification. We present computational methods for matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) spectral data preprocessing and peak selection. In particular, we propose a novel method that combines ant colony optimization (ACO) with support vector machines (SVM) to select a small set of useful peaks.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
1367-4811
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:day |
1
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pubmed:volume |
23
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
619-26
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pubmed:dateRevised |
2009-11-4
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pubmed:meshHeading |
pubmed-meshheading:17237065-Algorithms,
pubmed-meshheading:17237065-Carcinoma, Hepatocellular,
pubmed-meshheading:17237065-Computational Biology,
pubmed-meshheading:17237065-Humans,
pubmed-meshheading:17237065-Liver Cirrhosis,
pubmed-meshheading:17237065-Liver Neoplasms,
pubmed-meshheading:17237065-Models, Biological,
pubmed-meshheading:17237065-Molecular Weight,
pubmed-meshheading:17237065-Peptides,
pubmed-meshheading:17237065-Proteomics,
pubmed-meshheading:17237065-Spectrometry, Mass, Matrix-Assisted Laser...,
pubmed-meshheading:17237065-Tumor Markers, Biological
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pubmed:year |
2007
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pubmed:articleTitle |
Peak selection from MALDI-TOF mass spectra using ant colony optimization.
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pubmed:affiliation |
Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC 20057, USA. hwr@georgetown.edu
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, N.I.H., Extramural
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