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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1992-3-19
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pubmed:abstractText |
1. Hemoglobin (Hb) switching in the perinatal life of wild mouflon (Ovis musimon) was characterized by the replacement of Hb F by 60% levels of Hb C, and subsequently of Hb C by Hb B. 2. The recently discovered Hb M variant was not replaced by Hb C; thus, Hb BM heterozygote newborns synthesized 30% Hb C at the expense of Hb B. 3. Hybrid B mouflon x B sheep synthesized only 5% Hb C at birth but were able to produce 30% Hb C in adult life following induced anemia. 4. Adult BB and BM mouflons, after the same extent of induced anemia, synthesized HB C levels similar to those produced at birth. The results indicate a mouflon beta-globin gene cluster arrangement similar to those of sheep and goat, the beta C gene having an intermediate expression. Results also suggest a selective disadvantage in hybrid animals.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0300-9629
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
100
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
675-80
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pubmed:dateRevised |
2008-10-30
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pubmed:meshHeading |
pubmed-meshheading:1723669-Animals,
pubmed-meshheading:1723669-Fetal Hemoglobin,
pubmed-meshheading:1723669-Hemoglobin C,
pubmed-meshheading:1723669-Hybridization, Genetic,
pubmed-meshheading:1723669-Kinetics,
pubmed-meshheading:1723669-Phenotype,
pubmed-meshheading:1723669-Ruminants,
pubmed-meshheading:1723669-Sheep
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pubmed:year |
1991
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pubmed:articleTitle |
Kinetics of the ontogenic and reversible hemoglobin switching in the mouflon (Ovis musimon) and sheep x mouflon hybrid.
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pubmed:affiliation |
Istituto di Fisiologia Generale e Chimica Biologica, Università di Sassari, Italy.
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pubmed:publicationType |
Journal Article,
Comparative Study
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