Linked Life Data

17226917

Source:http://linkedlifedata.com/resource/pubmed/id/17226917

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2
pubmed:dateCreated
2007-1-17
pubmed:abstractText
The early hypersensitivity reaction and late bone marrow depression are well-known side-effects of azathioprine, whereas interstitial pneumonia is a rare complication. A 40-year old male patient had been treated with azathioprine in consequence of extensive ulcerative colitis for 10 years. He then complained of 7 d of fever, cough and catarrhal signs, without symptoms of active colitis. Opportunistic infections were ruled out. The chest X-ray, CT and lung biopsy demonstrated the presence of interstitial inflammation. Azathioprine therapy was discontinued as a potential source of the pulmonary infiltrate. In response to steroid therapy, and intensive care, the pulmonary infiltrate gradually decreased within 4 wk. Three months later, his ulcerative colitis relapsed, and ileo-anal pouch surgery was performed. In cases of atypical pneumonia, without a proven infection, azathioprine-associated interstitial pneumonitis may be present, which heals after withdrawal of the drug.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
1007-9327
pubmed:author
pubmed:issnType
Print
pubmed:day
14
pubmed:volume
13
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
316-9
pubmed:meshHeading
pubmed:year
2007
pubmed:articleTitle
A case of interstitial pneumonitis in a patient with ulcerative colitis treated with azathioprine.
pubmed:affiliation
First Department of Medicine, Faculty of Medicine, University of Szeged, Koranyi fasor 8, H-6701, Szeged, POB 427, Hungary. agyferi@in1st.szote.u-szeged.hu
pubmed:publicationType
Journal Article, Case Reports