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rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
2
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pubmed:dateCreated |
2007-3-14
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|
pubmed:abstractText |
Recent study suggested that endothelial progenitor cells (EPCs), a novel therapeutic approach for endothelial dysfunction, present limited antithrombogenic potentials. However, few attempts have been done to improve the antithrombogenic potentials of EPCs. Our previous study proved that in vitro shear stress contributes to the increase in t-PA production by human EPCs. Here, we further investigated whether in vitro shear stress contributes to the secretion of antithrombogenic substances including plasminogen activator inhibitor-1 (PAI-1) and prostaglandin I(2) (PGI(2)) by human EPCs.
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pubmed:language |
eng
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pubmed:journal |
|
|
pubmed:citationSubset |
IM
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|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
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pubmed:month |
Apr
|
|
pubmed:issn |
0929-5305
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pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:volume |
23
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pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
121-7
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|
pubmed:meshHeading |
pubmed-meshheading:17221326-6-Ketoprostaglandin F1 alpha,
pubmed-meshheading:17221326-Cells, Cultured,
pubmed-meshheading:17221326-Endothelial Cells,
pubmed-meshheading:17221326-Epoprostenol,
pubmed-meshheading:17221326-Humans,
pubmed-meshheading:17221326-Leukocytes, Mononuclear,
pubmed-meshheading:17221326-Plasminogen Activator Inhibitor 1,
pubmed-meshheading:17221326-Rheology,
pubmed-meshheading:17221326-Stem Cells,
pubmed-meshheading:17221326-Stress, Mechanical
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|
pubmed:year |
2007
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|
pubmed:articleTitle |
In vitro shear stress modulates antithrombogenic potentials of human endothelial progenitor cells.
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pubmed:affiliation |
Department of Cardiology, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou 510080, China.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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