|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
6
|
|
pubmed:dateCreated |
2007-5-1
|
|
pubmed:abstractText |
MYH is a member of the DNA base excision repair (BER) pathway and mutations of this gene predispose to the development of colorectal neoplasia in an autosomal recessive transmission pattern. Our objective was to determine the significance of MYH mutations in a series of Canadian patients with multiple adenomas.
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
May
|
|
pubmed:issn |
0022-4790
|
|
pubmed:author |
|
|
pubmed:copyrightInfo |
Copyright 2007 Wiley-Liss, Inc.
|
|
pubmed:issnType |
Print
|
|
pubmed:day |
1
|
|
pubmed:volume |
95
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
499-506
|
|
pubmed:dateRevised |
2007-7-10
|
|
pubmed:meshHeading |
pubmed-meshheading:17219385-Adenocarcinoma,
pubmed-meshheading:17219385-Adenoma,
pubmed-meshheading:17219385-Adenomatous Polyposis Coli,
pubmed-meshheading:17219385-Adult,
pubmed-meshheading:17219385-Aged,
pubmed-meshheading:17219385-Colorectal Neoplasms,
pubmed-meshheading:17219385-DNA, Neoplasm,
pubmed-meshheading:17219385-DNA Glycosylases,
pubmed-meshheading:17219385-DNA Mutational Analysis,
pubmed-meshheading:17219385-Female,
pubmed-meshheading:17219385-Genetic Predisposition to Disease,
pubmed-meshheading:17219385-Germ-Line Mutation,
pubmed-meshheading:17219385-Heterozygote,
pubmed-meshheading:17219385-Humans,
pubmed-meshheading:17219385-Male,
pubmed-meshheading:17219385-Middle Aged,
pubmed-meshheading:17219385-Pedigree
|
|
pubmed:year |
2007
|
|
pubmed:articleTitle |
Germline MYH mutations in a clinic-based series of Canadian multiple colorectal adenoma patients.
|
|
pubmed:affiliation |
Centre for Cancer Genetics, Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada.
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
