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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
6
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pubmed:dateCreated |
2007-5-17
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pubmed:abstractText |
VCAM-1 plays a major role in the chronic inflammatory processes present in vulnerable atherosclerotic plaques. The residues 75-84 (B2702-p) and 84-75/75-84 (B2702-rp) of the major histocompatibility complex-1 (MHC-1) molecule B2702 were previously shown to bind specifically to VCAM-1. We hypothesised that radiolabelled B2702-p and B2702-rp might have potential for the molecular imaging of vascular cell adhesion molecule-1 (VCAM-1) expression in atherosclerotic plaques.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
1619-7070
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
34
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
830-40
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pubmed:meshHeading |
pubmed-meshheading:17219135-Adjuvants, Immunologic,
pubmed-meshheading:17219135-Animals,
pubmed-meshheading:17219135-Aorta,
pubmed-meshheading:17219135-Atherosclerosis,
pubmed-meshheading:17219135-Autoradiography,
pubmed-meshheading:17219135-Azo Compounds,
pubmed-meshheading:17219135-Diagnostic Imaging,
pubmed-meshheading:17219135-Disease Models, Animal,
pubmed-meshheading:17219135-Dose-Response Relationship, Drug,
pubmed-meshheading:17219135-Inflammation,
pubmed-meshheading:17219135-Iodine Radioisotopes,
pubmed-meshheading:17219135-Major Histocompatibility Complex,
pubmed-meshheading:17219135-Peptide Fragments,
pubmed-meshheading:17219135-Rabbits,
pubmed-meshheading:17219135-Vascular Cell Adhesion Molecule-1
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pubmed:year |
2007
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pubmed:articleTitle |
Molecular imaging of vascular cell adhesion molecule-1 expression in experimental atherosclerotic plaques with radiolabelled B2702-p.
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pubmed:affiliation |
INSERM, U340, Radiopharmaceutiques Biocliniques, 38700, La Tronche, France.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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